Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
8 citations,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
2 citations,
January 2014 in “Springer eBooks” The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
5 citations,
January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.
73 citations,
April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
April 2018 in “Journal of Investigative Dermatology” Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
47 citations,
March 2022 in “Frontiers in cellular and infection microbiology” Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
43 citations,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
May 2018 in “Journal of Investigative Dermatology” DNMT3A is crucial for healthy skin and hair growth.
November 2023 in “Klìtinna ta organna transplantologìâ” MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.
80 citations,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
301 citations,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
4 citations,
January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
March 2024 in “Frontiers in genetics” Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
12 citations,
May 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Activating TRPV3 channels stops hair growth by killing hair follicle cells.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
February 2024 in “Scientific reports” Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
3 citations,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
52 citations,
March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
21 citations,
October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
2 citations,
March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.