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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Hair growth and pigmentation in mice involve specific stages crucial for research.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Lactate production is important for activating hair growth stem cells.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

EGF controls hair growth by regulating hair follicles' growth phases.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Mutant mice help researchers understand hair growth and related genetic factors.

Follistatin helps hair growth and cycling, while activin prevents it.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.

FGF5 gene mutations cause long hair in domestic cats.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

HFMs can help study hair growth and test potential hair growth drugs.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.