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Exosomes may improve skin, scars, hair growth, and fat grafts in plastic surgery, but more research is needed.

Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.

Licorice has many health benefits but should be used carefully due to possible side effects.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Electrospun 3D nanofibrous materials show promise for bone regeneration in orthopaedics.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

Injecting a person's own fat stem cells into their skin can make it look younger and improve double eyelids for over a year.

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

Injecting a mix of human skin and hair cells into mice can grow new hair.

The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.

Hair restoration techniques have improved but still rely on limited donor hair, with new methods like cloning and gene therapy being explored.

The best results in surgical hair restoration come from careful techniques, optimal use of limited hair supply, correct hair direction, saving hair for key areas, understanding scarring effects, and adjusting hair graft density.

Effective repair of bad hair transplants requires skilled techniques and careful use of donor hair, with strategies like reimplantation and camouflage, and new methods to minimize scarring.

Hair transplantation has evolved to refined techniques like FUE and FUT, with Finasteride and Minoxidil as the only other proven treatments for hair loss.

Lower hairlines using the rule of thirds can be used in hair transplants due to improved techniques.

Follicular-unit grafting is an effective hair transplant method that looks natural and has a high success rate.