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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.

Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.

Topical vitamin D is effective in treating vitiligo with few side effects.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

The document explains how hair follicles develop, their structure, and how they grow.

Diagnosing and treating PCOS is complex due to differing criteria and requires a team approach.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.