research Perspectives of Kennedy's Disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
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research Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Estrogens And The Hair Follicle
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
research Autoimmunity and Autoimmune Co-Morbidities in Psoriasis
Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.
research Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance
Thyroid function affects skin health, with a complex interaction between the two.
research Generation and Characterization of Rat Liver Stem Cell Lines and Their Engraftment in a Rat Model of Liver Failure
Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
research A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research Quercetin and Polycystic Ovary Syndrome: Current Evidence and Future Directions - A Systematic Review
Quercetin may help with PCOS symptoms, but more research is needed.
research Experimental and Clinical Pharmacology of Ziziphus Jujuba Mills
Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Clinical Relevance of Testosterone and Dihydrotestosterone Metabolism in Women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Exploring the Brain-Skin Connection: Leads and Lessons from the Hair Follicle
Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
research 5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction
Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research An Important Role of Cutaneous Lymphatic Vessels in Coordinating and Promoting Anagen Hair Follicle Growth
Skin lymphatic vessels are essential for hair growth.
research 5α-Reductase Type 1 Inhibition of Oryza Sativa Bran Extract Prepared by Supercritical Carbon Dioxide Fluid
Rice bran extract might help prevent hair loss.
research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Bisphenol-A Antagonizes the Rapidly Modulating Effect of Dihydrotestosterone on Spinogenesis and Long-Term Potentiation of Hippocampal Neurons
Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
research Expression of Sex-Determining Genes in the Scalp of Men with Androgenetic Alopecia
Sex-determining genes may affect male baldness.
research Melatonin Supplement Induced Hair Follicle Development in Offspring Rex Rabbits
Melatonin given to pregnant rabbits improved their babies' fur quality.
research Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review
Caffeine improves hair growth, thickness, and reduces shedding.
research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Functional Analysis of VDR Gene Mutation R343H in a Child with Vitamin D-Resistant Rickets with Alopecia
The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.
research The Use of Phosphodiesterase Inhibitors for the Treatment of Alopecia
Caffeine shows promise for treating some types of hair loss, but more research is needed.
research A Multicenter Evaluation of 10% Sulfacetamide Sodium in a 10% Urea Vehicle Scalp Treatment Lotion and a 10% Urea Deep Cleansing Antibacterial Shampoo for the Treatment of Seborrheic Dermatitis of the Scalp
The lotion and shampoo effectively treated scalp seborrheic dermatitis.
research The Role of Topical Vitamin D in Vitiligo: A Narrative Literature Review
Topical vitamin D is effective in treating vitiligo with few side effects.