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Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Tofacitinib may help treat severe hair loss, but more research is needed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

The HR protein's role as a repressor is essential for controlling hair growth.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

A gene called HDAC9 might be a new factor in male-pattern baldness.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.