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Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Placental growth factor may help treat hair loss.

Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Tight hairstyles, especially on chemically treated hair, can cause reversible hair loss if caught early but may become permanent if not addressed.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Most hair loss in captive rhesus macaques is likely due to environmental and behavioral factors.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.

Immune cells affect hair growth and could lead to new hair loss treatments.

Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.

The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

Finasteride helps hair growth by decreasing cell death in hair follicles.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.