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5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

A plant extract was found to effectively block an enzyme related to male hormone-related diseases.

Bitter melon extract may help prevent hair loss and can be used in cosmetic products.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Some common medications can harm male fertility, but many effects can be reversed.

Finasteride doesn't affect erections much, but may decrease libido in men.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Two lotions used day and night may be a good alternative to minoxidil for hair loss, with better cosmetic effects and tolerance.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.