research Finasteride Inhibits Melanogenesis Through Regulation of the Adenylate Cyclase in Melanocytes and Melanoma Cells
Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
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research Determination of Finasteride in Tablet Form by Liquid Chromatography and Its Analytical Method Validation
Validated method reliably measures finasteride in tablets using liquid chromatography.
research Research Brief: Self-Reports of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men
Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
research Screening of Euphorbiaceae Plant Extracts for Anti-5α-Reductase Activity
Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Differential Effects of Wnt5a on the Proliferation, Differentiation, and Inflammatory Response of Keratinocytes
Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.
research Plants as Potential Active Components in Treatment of Androgenetic Alopecia
Plant extracts may help treat hormone-related hair loss.
research Pharmacokinetic Interaction Between Finasteride and Terazosin, but Not Finasteride and Doxazosin
Finasteride interacts with terazosin, but not doxazosin; caution needed.
research Bioequivalence Study of Two Different Coated Tablet Formulations of Finasteride in Healthy Volunteers
Two finasteride tablet types are equally effective and can be swapped.
research Determination of Rat 5α-Reductase Type 1 Isozyme Activity and Its Inhibition by Novel Steroidal Oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Androgenetic Alopecia in Men
AGA treated with finasteride, minoxidil, and hair transplantation.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Long-Term Treatment with Finasteride Induces Apoptosis and Pathological Changes in Female Mice
Finasteride causes harmful organ changes in female mice.
research Androgenetic Alopecia (Male Pattern Hair Loss) in the United States: What Treatments Should Primary Care Providers Recommend?
Use minoxidil or finasteride first, then try HairMax LaserComb if needed.
research Regarding Prostate-Specific Antigen: Let's Not Shoot the Messenger
The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
research The Role of Androgens in Hidradenitis Suppurativa and the Potential Benefits of Antiandrogen Therapy
Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Male Androgenetic Alopecia Treated With Finasteride
Finasteride 1mg daily effectively increases hair growth and slows hair loss in men with male pattern baldness over two years.
research Formononetin: Novel Treatment for Androgenetic Alopecia
Formononetin, found in red clover, may treat hair loss with fewer side effects.
research What Should the Hair Clinician Know About Hair Transplants?
Hair transplants are effective for male and female pattern baldness, have evolved in technique, and require careful planning for natural results and managing complications.
research Letter to the Editor: Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss
Finasteride use may cause sexual dysfunction; more research needed.
research FGF Signaling for Hair Cycle Resting Phase Alleviates Radiation Alopecia
FGF18 treatment during hair's resting phase can protect against hair loss from radiation.
research Hair Growth as Anti-Aging
Anti-aging treatments like hair transplants, minoxidil, and finasteride effectively promote hair growth.
research Risk of Estrogen-Driven Malignancies in Females on 5-Alpha Reductase Inhibitors
Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.
research Longitudinal Clinical Course in Patients With 5α-Reductase Type 2 Deficiency Treated With Testosterone and Dihydrotestosterone During Infancy and Puberty
Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.
research 5-Alpha Reductase Inhibitors: New Evidence on Benefits and Harms Beyond Benign Prostatic Hyperplasia
5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.
research An Efficient Synthesis of Dutasteride: Utilizing Benzoyl Group as Novel Lactamic Protecting Group
Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.
research Finasteride in the Treatment of Female Androgenic Alopecia
Finasteride may help postmenopausal women with hair loss but is not effective for all and should be used cautiously in premenopausal women.
research Evaluation of Polymorphism Influence in Finasteride
Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.