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14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

Costunolide helps human hair cells grow and can stimulate hair growth in mice.

Genes and hormones cause hair loss, with four genes contributing equally.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Minoxidil slows down keratinocyte growth without being toxic.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Lowering testosterone speeds up wound healing in male mice.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

A new compound effectively inhibits human 5α-reductase 1.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Finasteride negatively affects fish reproduction and gonadal development.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Phenylephrine may help prevent hair loss from pulling on the hair roots.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Testosterone's muscle-building effects do not require its conversion to DHT.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Rats had lasting erectile problems after stopping a certain medication.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.