research Role of the Wnt Signaling Pathway in Keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
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research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research Scarring Hair Follicle Destruction Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research Hair Follicle Stem Cell Progeny Heal Blisters While Pausing Skin Development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Conditioned Media Derived from Mesenchymal Stem Cell Cultures: The Next Generation for Regenerative Medicine
Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
research In Vitro Induction of Hair Follicle Signatures Using Human Dermal Papilla Cells Encapsulated in Fibrin Microgels
Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.
research Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632
A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
research Regeneration of a Bioengineered 3D Integumentary Organ System from iPS Cells
Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.
research Ginsenoside Rg4 Enhances the Inductive Effects of Human Dermal Papilla Spheres on Hair Growth Via the AKT/GSK-3β/β-Catenin Signaling Pathway
Ginsenoside Rg4 from ginseng may help hair growth by activating certain cell signals.
research Hydrogel-Mediated Extracellular Vesicles for Enhanced Wound Healing: The Latest Progress and Their Prospects for 3D Bioprinting
Hydrogels combined with extracellular vesicles and 3D bioprinting improve wound healing.
research Advancing Skin Model Development: A Focus on a Self-Assembled, Induced Pluripotent Stem Cell-Derived, Xeno-Free Approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Comparative Analysis of Biological Properties of Large-Scale Expanded Adult Neural Crest-Derived Stem Cells Isolated from Human Hair Follicle and Skin Dermis
Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells
Vitamin B3 may help prevent hair loss and promote hair growth by protecting scalp cells from stress and reducing hair growth-blocking proteins.
research Human Fibroblast-Derived Matrix Hydrogel Accelerates Regenerative Wound Remodeling Through Interactions With Macrophages
A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
research KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
research Feasibility of Repairing Full-Thickness Skin Defects by iPSC-Derived Epithelial Stem Cells Seeded on a Human Acellular Amniotic Membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Ganoderma Lucidum Extract Attenuates Corticotropin-Releasing Hormone Induced Cellular Senescence in Human Hair Follicle Cells
Ganoderma lucidum extract may help treat stress-related hair loss.
research Characterization of Type II Rickets Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor
The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
research Y27632 Promotes Proliferation via EGFR Signaling in a Newly Isolated and Characterized Human Primary Sebocyte Cell Line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
research New Insights Into Human Hair: SAXS, SEM, TEM, and EDX for Alopecia Areata Investigations
Alopecia Areata causes significant structural and compositional changes in hair.
research Mechanical Stimulation of Human Hair Follicle Outer Root Sheath Cultures Activates Adjacent Sensory Neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research Establishment and Characterization of Matched Immortalized Human Frontal and Occipital Scalp Dermal Papilla Cell Lines from Androgenetic Alopecia
Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
research Gene Therapy for Alopecia in Type II Rickets Model Rats Using Vitamin D Receptor-Expressing Adenovirus Vector
Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Hematopoiesis in Mouse Cultures
Hair follicle cells help maintain and support stem cells and blood cell formation.
research Effect of N-Acetylcysteine on Hair Follicle Changes in Mouse Model of Cyclophosphamide-Induced Alopecia: Histological and Biochemical Study
N-acetylcysteine may prevent hair loss caused by chemotherapy.