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TGF-β2 plays a key role in human hair growth and development.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Mice with human gene experienced hair loss when treated with DHT.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Quercetin may help with PCOS symptoms, but more research is needed.

Melatonin may help treat PCOS symptoms in rats.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Minoxidil helps regrow hair in female pattern hair loss, but more research needed for other treatments.

Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

Prolactin may affect hair growth differently based on gender and scalp area.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.