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      community How much time does it need to pass for a hair follicle to be considered "unrecoverable"?

      in Chat  26 upvotes 8 months ago
      A user who experienced hair loss and stopped finasteride 4.5 years ago is considering restarting treatment with finasteride and oral minoxidil, questioning if their hair follicles are still recoverable. Responses suggest that hair follicles may not die and can potentially be revived even after many years, with some users sharing personal success stories using treatments like minoxidil, finasteride, microneedling, and RU58841.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 8 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community People here just don't know what they are letting themselves in for!

      in Chat  125 upvotes 8 months ago
      The conversation discusses hair loss treatments, emphasizing the importance of patience and sticking with a treatment for at least 12-18 months before judging its effectiveness or adding new treatments. Users share experiences and agree that introducing treatments too quickly can lead to panic and negative outcomes.

      community Tressless When They See Verteporfin Results

      in Transplants  182 upvotes 1 year ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

      in Research/Science  112 upvotes 1 year ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community I am finally giving up on my hair

      in Shaved/buzzed  57 upvotes 1 year ago
      User tried Minoxidil and Finasteride for hair loss with no success and considers giving up. Others suggest continuing treatment, trying hair transplant, or embracing baldness.

      community 1 year of regular fin after years of anxiety

      in Update  94 upvotes 1 year ago
      User GreatCanuck experienced hair regrowth after using finasteride for a year, reducing anxiety about hair loss. Others in the conversation shared similar positive experiences and discussed family members using the treatment.

      community Study: Peppermint oil more effective than minoxidil, thoughts?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses a claim that peppermint oil is more effective than minoxidil for hair loss, with one user mentioning using a mix of peppermint and rosemary oils as a treatment. Some users are skeptical, while others show interest in the potential of peppermint oil.

      community Using Rosemary and other essential Oils

      in Product  8 upvotes 2 years ago
      The conversation discusses creating a mix of essential oils for hair regrowth, questioning the proper mix ratio for single or multiple oils. It also mentions using finasteride and minoxidil for hair loss treatment, alongside oils, shampoos, and microneedling to improve scalp conditions for hair regrowth.

      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  288 upvotes 3 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Have you guys heard about topical melatonin?

      in Research  7 upvotes 4 years ago
      Topical melatonin may improve hair density and thickness, and reduce hair loss and seborrhea with no significant side effects. The user made their own melatonin solution for hair treatment.

      community Only 10 more days until cassiopea releases their 12 month results for CB-03-01 our best hope of an alternative to finasteride

      in Finasteride  151 upvotes 5 years ago
      The conversation discusses anticipation for CB-03-01, a potential new hair loss treatment that may be more effective and have a cleaner safety profile than finasteride. Users are hopeful but cautious, discussing current treatments like minoxidil, nizoral, and dermarolling, and the possibility of combining them with CB-03-01 for better results.

      community 12 months of progress on fin (and 10 months microneedling)

      in Update  367 upvotes 5 years ago
      A user's 12 month progress on finasteride and 10 months of microneedling for hair loss treatment, which has resulted in improved temple areas with no side effects from the finasteride. They have not used minoxidil yet but are considering it for further gains. DHT blocking drugs such as finasteride and dutasteride are recommended to maintain regrowth results.

      community Discussion on Finasteride and life.

      in Chat  162 upvotes 1 month ago
      Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

      community 3.5-4 month progress is this hyper response?

      in Progress Pictures  29 upvotes 4 months ago
      A user shared their 3.5-4 month progress using Topical Minoxidil, Oral Finasteride, Keto 1%, and Dermastamp, reporting positive results despite some shedding and flaking. Replies praised the progress and inquired about the treatment routine and temple condition.

      community Do any of you guys feel like your 20s have been wasted?

      in Chat  184 upvotes 6 months ago
      A user expressed frustration about hair loss and its impact on their 20s, mentioning financial struggles and mental health concerns. Responses included advice on positive thinking, self-improvement, and seeking treatment options like Minoxidil and finasteride.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Why anecdotal evidence is so valued around here?

      in Chat  18 upvotes 7 months ago
      The conversation discusses why personal stories about hair loss treatments like Minoxidil and finasteride are often taken more seriously than scientific evidence in certain forums. People tend to believe what they want and use others' experiences to support their own views on treatment effectiveness and side effects.

      community "Dutasteride Ruined My Hairline!"

      in Finasteride/Dutasteride  36 upvotes 9 months ago
      The user has been on dutasteride for six months and experienced significant hair shedding, especially at the hairline, and is seeking advice. Some suggest continuing the treatment and being patient, while others share mixed experiences with dutasteride and consider switching back to finasteride or adding other treatments like RU58841.

      community 5 years on Finasteride, 1.5 years on Minoxidil Foam

      in Progress Pictures  706 upvotes 9 months ago
      The user has been using finasteride for five years and minoxidil foam for 1.5 years to combat hair loss, experiencing significant regrowth after an initial shedding phase with minoxidil. They shared progress pictures and discussed treatment experiences, including the addition of minoxidil to their regimen after noticing reduced efficacy with finasteride alone.

      community 19 yo destroyed hairline even though using Fin/min/microneedling for 16months/11months/3months … Idk what to do.

      in Progress Pictures  257 upvotes 10 months ago
      A 19-year-old has been using finasteride, minoxidil, and microneedling to treat hair loss with no regrowth, feeling mentally affected by it. Advice given includes continuing treatment, considering a hair transplant, addressing potential vitamin deficiencies, and possibly switching to dutasteride or adding ketoconazole shampoo.

      community Dutasteride 1 year regression. Depressing. (With pictures for proof)

      in Progress Pictures  14 upvotes 11 months ago
      A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

      community 35m 1.5 months on oral fin/min is it too good to be true?

      in Progress Pictures  161 upvotes 1 year ago
      A 35-year-old man, balding since 18, has seen growth of small, almost white hairs all over his scalp after 1.5 months on oral finasteride and minoxidil. Users suggest sticking with the treatment for a year, adding microneedling, and potentially trying RU58841 or dutasteride.