The Rhino Mouse: Retinoid Effects on a Model of Keratin Accumulation

The study focused on the rhino mouse, which exhibited skin characterized by large cysts, including superficial utricles derived from hair canals and deeper cysts from hair root sheath epithelium. These cysts were lined with keratinizing epithelium, and the study explored the effects of retinoids on this model of keratin accumulation. The research provided insights into the histological changes induced by retinoids, contributing to the understanding of keratinization and potential therapeutic approaches for skin conditions involving keratin accumulation.