The Pathobiology of Skin Aging

April 2020 in “ American Journal Of Pathology ”

Eleanor Russell‐Goldman, George J. Murphy

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Research cited in this study

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research Differential Distribution of the Epigenetic Marker 5-Hydroxymethylcytosine in Hair Follicle Stem Cells During Bulge Activation

4 citations, February 2019 in “Journal of Cutaneous Pathology”

The marker 5-hmC changes in hair follicle stem cells when they start to grow.

research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta

96 citations, December 2018 in “Immunity”

Targeting TGFβ can improve skin immunity in older people.

research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

96 citations, July 2014 in “Cold Spring Harbor Perspectives in Medicine”

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

research Human Skin Stem Cells and the Aging Process

143 citations, September 2008 in “Experimental gerontology”

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

research The Human Skin as a Hormone Target and an Endocrine Gland

146 citations, January 2004 in “Hormones”

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin

196 citations, May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Sebocytes play a key role in controlling androgen levels in human skin.