The detection of apoptosis and bcl<sub>2</sub> in isolated secondary mohair follicles (growing and quiescent), cultured <i>in vitro</i> in the presence or absence of biotin
January 1999
in “
Proceedings of the British Society of Animal Science
”
TLDR Biotin helps maintain hair follicle growth by affecting cell death and survival signals.
The study investigated the presence of apoptosis and the expression of the apoptosis inhibitor bcl 2 in isolated secondary mohair follicles, both growing and quiescent, cultured in vitro with or without biotin supplementation. It was found that biotin deficiency was previously shown to reduce follicle viability and thymidine uptake. The research aimed to understand how biotin affects apoptosis and bcl 2 expression, which are crucial for hair growth and follicle viability. The findings suggested that biotin plays a role in maintaining follicle growth by potentially influencing apoptosis and bcl 2 expression.
