TLDR A 15-year-old girl with hypothyroidism had excess hair and skin issues due to blocked hair follicles.
A 15-year-old Japanese girl with juvenile hypothyroidism experienced hypertrichosis and hyperkeratosis on her back and upper arms. Rolled hairs were observed beneath a thin translucent horny layer, caused by a follicular keratin plug that impeded the growth of miniature hairs.
50 citations
,
July 2008 in “British Journal of Dermatology” 138 citations
,
March 2007 in “Experimental cell research” Only a few hair-specific keratins are linked to inherited hair disorders.
276 citations
,
January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
199 citations
,
January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
29 citations
,
April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
