Hormone-Induced Aberrations in Electromagnetic Adhesion Signaling as a Developmental Factor of Androgenetic Alopecia

This scientific paper proposes a hypothesis about the role of hormones, specifically androgens, in the development of androgenetic alopecia (AGA), or male pattern baldness. The authors suggest that an increase in dihydrotestosterone (DHT) production inhibits cell mitosis in the dermal papilla and contributes to programmed cell death, leading to miniaturization of hair follicles. They also propose that electromagnetic adhesion forces weaken in the inhibited mitosis state, leading to weaker electrical attraction between undifferentiated stem cells and the dermal papilla, which can cause damage or death of cells and miniaturization of hair follicles. The paper also discusses the functional role of insulin resistance in AGA and suggests that early alopecia can be one marker of insulin resistance and endothelial dysfunction.