Hormonal changes and hair growth during treatment of hirsutism with cimetidine.

A study conducted on 4 women with hirsutism and 3 women with peptic ulcer as controls examined the effects of cimetidine on hair growth over 9 months. While hair growth slowed in all treated women, the results were not statistically significant. A notable finding was a significant decrease in urine 17-ketosteroids, but no substantial changes were observed in plasma levels of testosterone, 17-beta estradiol, progesterone, FSH, LH, and prolactin. The study concluded that cimetidine did not have a significant impact on hair growth to warrant its use in treating hirsutism.