Expression of androgen receptors in skin appendage tumors: An immunohistochemical study
April 1995
in “
Journal of Cutaneous Pathology
”
TLDR Androgen receptors are found in some skin tumors but not in hair follicle tumors.
The study investigated androgen receptor (AR) expression in normal skin and 52 skin appendage tumors using immunohistochemical methods. AR was found in the nuclei of seboblasts and some sebocytes in normal skin, with variable expression in eccrine and apocrine glands, but not in hair follicles or epidermis. In sweat gland tumors, AR was present in some chondroid syringomas but absent in others. Benign sebaceous tumors showed AR expression, whereas sebaceous epitheliomas and carcinomas did not. Hair follicle tumors generally lacked AR expression, except for AR-positive sebaceous glands in steatocystomas.
