TLDR Alkaline phosphatase activity in Beagle dog hair follicles is weakest in anagen and strongest in telogen.
This study investigated alkaline phosphatase activity in hair follicles during different hair cycle stages (anagen, catagen, and telogen) in 9 male Beagle dogs of varying ages over 1 year. Skin biopsies were analyzed using Gomori's calcium cobalt method. The findings revealed that during the anagen stage, the dermal papilla showed a weak or negative reaction to alkaline phosphatase, which was unexpected. In contrast, a positive reaction was observed during the catagen stage, and a strong positive reaction was noted in the telogen stage, with activity present throughout the dermal papilla, not just in blood vessels.
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